Oxy-TC DTI¶
Analysis of Diffusion Tensor Imaging (DTI) data from the Oxy-TC trial.
Overview¶
Oxy-TC DTI is a Python project designed for the analysis of DTI data from the Oxy-TC trial, a multi-center randomized clinical trial on the use of PbtO2 probe in neuro-ICU for TBI patients.
This project is part of an ancillary study of the trial. Initially, the Oxy-TC's primary endpoint was to link the volume of MD lesions, but it was later changed to neurological outcome (assessed with Glasgow Outcome Scale Extended score at 6 months). The ancillary study focuses on the initial primary endpoint: assessing whether PbtO2 reduces the volume of DTI lesions. As a secondary endpoint, it examines the relationship between lesion volume and neurological outcomes.